Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538425 | 0.79 | TERT (0.48) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27584020 | 0.76 | TPMT (0.42) | TPMTHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL28103068 | 0.71 | ALDH1A1 (0.44) | TPMTHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL7238156 | 0.67 | FFAR1 (0.54) | TPMTCYP1A2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL5444019 | 0.65 | HPGD (0.38) | TPMTMAPTHPGDHDAC3HDAC4 | |
| Acetone SCHEMBL9722029 | 0.65 | TPMT (0.58) | TPMTHPGDHTTNPSR1CYP3A4 | |
| SCHEMBL30865854 | 0.64 | ALDH1A1 (0.45) | TPMTMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL29023726 | 0.64 | HDAC3 (0.47) | TPMTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11974562 | 0.64 | TPMT (0.56) | TPMTMAPTHPGDHTTNPSR1 | |
| Acetic Acid SCHEMBL27834373 | 0.63 | TPMT (0.63) | TPMTHPGDALDH1A1GPR35KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |