Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470876 | 0.78 | TERT (0.49) | TERTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9494565 | 0.77 | TERT (0.43) | TERTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8538425 | 0.77 | TERT (0.48) | TERTMEN1KMT2AALDH1A1PARP1 | |
| SCHEMBL24523122 | 0.74 | FFAR1 (0.48) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL2298661 | 0.73 | MEN1 (0.48) | TERTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8534162 | 0.73 | MTNR1A (0.56) | TERTLMNA | |
| SCHEMBL7165834 | 0.72 | TERT (0.43) | TERTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1821162 | 0.72 | — | — | |
| SCHEMBL1197606 | 0.72 | APEX1 (0.64) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL30996190 | 0.72 | TERT (0.43) | TERTMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |