Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYB | P10242 | 15/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543604 | 0.83 | MYB (0.70) | MYBCYP1A2KDM4EGAAMAPT | |
| SCHEMBL8543701 | 0.81 | MYB (0.70) | MYBMPOCYP1A2KDM4EGAA | |
| SCHEMBL8544234 | 0.71 | MYB (0.75) | MYBCYP1A2KDM4EGAAMAPT | |
| SCHEMBL8544137 | 0.70 | MEN1 (0.56) | MYBKDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL8112346 | 0.70 | MPO (0.56) | MYBMPOCYP1A2KDM4EGAA | |
| SCHEMBL8543562 | 0.69 | MYB (0.67) | MYBKDM4EGAAMAPTRAB9A | |
| SCHEMBL8541180 | 0.68 | MPO (0.59) | MYBMPOCYP1A2KDM4EGAA | |
| SCHEMBL8539407 | 0.68 | MYB (0.58) | MYBMPO | |
| SCHEMBL8810798 | 0.68 | MPO (0.51) | MYBMPOCYP1A2KDM4EGAA | |
| SCHEMBL8538269 | 0.68 | MYB (0.76) | MYBCYP1A2KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537949-B1 | Antiproliferative derivatives of 4H-naphtho 1,2-b pyran | LILLY CO ELI (GB) | 1998-07-01 | — | — | EP | disclosed |
| US-5284868-A | Naphthopyran derivatives; for autoimmune diseases, cancer | ELI LILLY AND COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| US-5281619-A | Administering naphtho(1,2-B)pyran derivatives | ELI LILLY AND COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0537949-A1 | Antiproliferative derivatives of 4H-naphtho 1,2-b pyran | LILLY INDUSTRIES LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |