Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538162 | 1.00 | TXNRD1 (0.41) | TXNRD1GSRMAPTHTTMEN1 | |
| SCHEMBL8542221 | 0.99 | TXNRD1 (0.41) | TXNRD1GSRMAPTHTTMEN1 | |
| SCHEMBL8543171 | 0.96 | TXNRD1 (0.39) | TXNRD1GSRMAPTHTTMEN1 | |
| SCHEMBL8542808 | 0.94 | TXNRD1 (0.37) | TXNRD1GSRMAPTHTTMEN1 | |
| SCHEMBL8542948 | 0.86 | TXNRD1 (0.39) | TXNRD1GSRMAPTHTTMEN1 | |
| SCHEMBL8537187 | 0.86 | TXNRD1 (0.39) | TXNRD1GSRMAPTHTTMEN1 | |
| SCHEMBL27372102 | 0.85 | TXNRD1 (0.37) | TXNRD1GSRMAPTHTTMEN1 | |
| SCHEMBL8538802 | 0.84 | TXNRD1 (0.40) | TXNRD1GSRMAPTHTTMEN1 | |
| SCHEMBL27357995 | 0.83 | TXNRD1 (0.37) | TXNRD1GSRMAPTHTTMEN1 | |
| SCHEMBL6936182 | 0.83 | SLC9A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |