Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469385 | 0.89 | HPGD (0.56) | HPGDALDH1A1USP2MAPK1SIGMAR1 | |
| SCHEMBL6474754 | 0.86 | HPGD (0.68) | HPGDALDH1A1USP2MAPK1SIGMAR1 | |
| SCHEMBL6560079 | 0.83 | HPGD (0.50) | HPGDALDH1A1MAPK1LMNAMTHFD2 | |
| SCHEMBL7685753 | 0.83 | ALDH1A1 (0.55) | HPGDALDH1A1LMNA | |
| SCHEMBL11605873 | 0.81 | HPGD (0.59) | HPGDALDH1A1USP2MAPK1SIGMAR1 | |
| SCHEMBL7047272 | 0.80 | HPGD (0.63) | HPGDALDH1A1MAPK1HDAC6LMNA | |
| SCHEMBL1263133 | 0.79 | HPGD (0.88) | HPGDALDH1A1USP2MAPK1SIGMAR1 | |
| SCHEMBL18228404 | 0.79 | HPGD (0.96) | HPGDALDH1A1USP2MAPK1SIGMAR1 | |
| SCHEMBL254870 | 0.79 | HPGD (0.96) | HPGDALDH1A1USP2MAPK1SIGMAR1 | |
| SCHEMBL17872147 | 0.79 | HPGD (0.61) | HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110878042-B | Preparation method of N-substituent piperidine-3-ketone | 新发药业有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-110878042-A | Preparation method of N-substituent piperidine-3-ketone | 新发药业有限公司 | 2020-03-13 | — | — | CN | disclosed |
| US-5755993-A | Peroxygen bleach composition activated by piperidone derivatives | COLGATE-PALMOLIVE CO. (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1997024429-A9 | PEROXYGEN BLEACH COMPOSITION ACTIVATED BY PIPERIDONE DERIVATIVES | — | 1997-09-04 | — | — | WO | disclosed |
| WO-1997024429-A1 | PEROXYGEN BLEACH COMPOSITION ACTIVATED BY PIPERIDONE DERIVATIVES | COLGATE-PALMOLIVE COMPANY (US) | 1997-07-10 | — | — | WO | disclosed |