SCHEMBL8538752

SCHEMBL8538752

CCc1cc(S(C)(=O)=O)c(S(C)(=O)=O)cc1C(=O)Cl

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.39
FLT1 P17948 1/20 0.35
FLT4 P35916 1/20 0.35
KDR P35968 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8542805 0.93 SLC9A1 (0.36) SLC9A1
SCHEMBL8540569 0.91 GAA (0.34) SLC9A1
SCHEMBL8543457 0.91 SLC9A1 (0.34) SLC9A1
SCHEMBL8543229 0.89 CNR1 (0.37) SLC9A1
SCHEMBL8543032 0.88 SLC9A1 (0.33) SLC9A1
SCHEMBL8542625 0.88 SLC9A1 (0.33) SLC9A1
SCHEMBL8542629 0.87 THRB (0.39) SLC9A1
SCHEMBL8544250 0.87 CA12 (0.35) SLC9A1
SCHEMBL8541283 0.85 CA12 (0.41)
SCHEMBL8541278 0.85 THRB (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744641-A Sulfonyl- or sulfinylbenzoylguanidine derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-04-28 US disclosed
EP-0514791-B1 Crystalline acid addition salts of diastereomerically pure 1-(2,2-dimethylpropionyloxy)-ethylester of 3-cephem-4-carboxylic acid HOECHST AG (DE) 1998-03-25 EP disclosed
EP-0514791-A2 Crystalline acid addition salts of both diastereomers of the 1-(2,2-dimethylpropionyloxy)-ethylester of 3-cephem-4-carboxylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-25 EP disclosed