Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542629 | 0.92 | THRB (0.39) | THRBSLC9A1 | |
| SCHEMBL8541278 | 0.90 | THRB (0.44) | THRB | |
| SCHEMBL8542805 | 0.89 | SLC9A1 (0.36) | SLC9A1 | |
| SCHEMBL8538752 | 0.89 | SLC9A1 (0.39) | SLC9A1 | |
| SCHEMBL8542394 | 0.89 | THRB (0.46) | THRB | |
| SCHEMBL8542373 | 0.85 | SLC9A1 (0.46) | CNR1SLC9A1LMNA | |
| SCHEMBL8540569 | 0.81 | GAA (0.34) | SLC9A1KDM4E | |
| SCHEMBL8543457 | 0.81 | SLC9A1 (0.34) | SLC9A1 | |
| SCHEMBL6934436 | 0.80 | SLC9A1 (0.57) | SLC9A1 | |
| SCHEMBL8542924 | 0.79 | EGLN1 (0.40) | THRBKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| US-5696167-A | 4-mercaptobenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-09 | — | — | US | disclosed |