Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539942 | 0.92 | MEN1 (0.34) | ABCB1MEN1LMNATP53CYP3A4 | |
| SCHEMBL8538642 | 0.87 | ALDH1A1 (0.39) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8539949 | 0.80 | KDM4E (0.33) | LMNATP53CYP3A4MAPTKMT2A | |
| SCHEMBL9038757 | 0.76 | CYP2C9 (0.40) | TP53CYP3A4MAPTSMN1; SMN2HPGD | |
| SCHEMBL8538767 | 0.76 | ITGB2 (0.30) | BCL2MCL1 | |
| SCHEMBL6961039 | 0.76 | SMN1; SMN2 (0.46) | ABCB1THRBMEN1TP53CYP3A4 | |
| SCHEMBL8538590 | 0.74 | ALDH1A1 (0.38) | MEN1MAPTKMT2AHPGDBCL2 | |
| SCHEMBL7377242 | 0.74 | GPR55 (0.36) | — | |
| SCHEMBL8538761 | 0.74 | NPC1 (0.47) | THRBLMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL6965606 | 0.74 | KDM4E (0.42) | THRBMEN1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |