Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539942 | 0.89 | MEN1 (0.34) | ALDH1A1KDM4ELMNAHPGDMAPT | |
| SCHEMBL8538765 | 0.87 | ABCB1 (0.31) | LMNAHPGDMAPTMEN1KMT2A | |
| SCHEMBL8539949 | 0.80 | KDM4E (0.33) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL8535732 | 0.79 | KDM4E (0.39) | ALDH1A1KDM4ELMNAHTTRECQL | |
| SCHEMBL9038757 | 0.78 | CYP2C9 (0.40) | ALDH1A1KDM4EHTTHPGDMAPT | |
| SCHEMBL7377242 | 0.77 | GPR55 (0.36) | TSHR | |
| SCHEMBL8538383 | 0.76 | MAOA (0.40) | ALDH1A1KDM4ELMNAHPGDMAPT | |
| SCHEMBL6952539 | 0.76 | TNKS (0.52) | ALDH1A1KDM4ELMNAHTTHPGD | |
| SCHEMBL9039510 | 0.75 | ELANE (0.34) | ELANE | |
| SCHEMBL6953696 | 0.75 | GPR55 (0.33) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |