Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | PGR | P06401 | 2/20 | 0.69 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.69 |
| ▸ | SHBG | P04278 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730817 | 0.92 | HIF1A (0.68) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL3638583 | 0.92 | HIF1A (0.68) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL607956 | 0.91 | HIF1A (0.72) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL10708917 | 0.89 | HIF1A (0.63) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL11814284 | 0.88 | HIF1A (0.81) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL603002 | 0.88 | HIF1A (0.69) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL9437393 | 0.87 | HIF1A (0.75) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL606810 | 0.86 | HIF1A (0.67) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL16020569 | 0.86 | HIF1A (0.78) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL606477 | 0.86 | HIF1A (0.66) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737062-B1 | WATER-IN-OIL LOTION CONTAINING A CORTICOSTEROID | GALDERMA SA (CH) | 1998-05-06 | — | — | EP | claimed |
| US-5653989-A | LOTION COMPRISING HYDROCORTISONE-21-ACETATE-17-PROPIONATE AND SELECTED WATER IN OIL EMULSION; FOR USE ON DRY SKIN | GALDERMA S.A. (CH) | 1997-08-05 | — | — | US | claimed |
| EP-0737062-B1 | WATER-IN-OIL LOTION CONTAINING A CORTICOSTEROID | GALDERMA SA (CH) | 1998-05-06 | — | — | EP | disclosed |
| US-5653989-A | LOTION COMPRISING HYDROCORTISONE-21-ACETATE-17-PROPIONATE AND SELECTED WATER IN OIL EMULSION; FOR USE ON DRY SKIN | GALDERMA S.A. (CH) | 1997-08-05 | — | — | US | disclosed |
| EP-0737062-A1 | WATER-IN-OIL LOTION CONTAINING A CORTICOSTEROID | GALDERMA S.A. (CH) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995017883-A1 | WATER-IN-OIL LOTION CONTAINING A CORTICOSTEROID | GALDERMA S.A. (CH) | 1995-07-06 | — | — | WO | disclosed |