SCHEMBL603002

SCHEMBL603002

C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)C(O)CCC(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 10/20 0.69
▸ LMNA P02545 2/20 0.69
▸ NR3C1 P04150 7/20 0.69
▸ SMN1; SMN2 Q16637 3/20 0.69
▸ CYP2C19 P33261 2/20 0.69
▸ HSD17B10 Q99714 2/20 0.69
▸ PGR P06401 2/20 0.69
▸ SERPINA6 P08185 2/20 0.69
▸ CYP3A4 P08684 2/20 0.69
▸ NFKB1 P19838 2/20 0.69
▸ MAPT P10636 2/20 0.69
▸ NR3C2 P08235 2/20 0.69
▸ SHBG P04278 1/20 0.69
▸ KMT2A Q03164 1/20 0.69
▸ AR P10275 1/20 0.64
▸ CHRM1 P11229 1/20 0.64
▸ PMP22 Q01453 1/20 0.60
▸ TSHR P16473 1/20 0.60
▸ POLB P06746 1/20 0.59
▸ GAA P10253 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL606810 0.95 HIF1A (0.67) HIF1ALMNANR3C1SMN1; SMN2CYP2C19
SCHEMBL606477 0.94 HIF1A (0.66) HIF1ALMNANR3C1SMN1; SMN2CYP2C19
SCHEMBL607956 0.91 HIF1A (0.72) HIF1ALMNANR3C1SMN1; SMN2CYP2C19
SCHEMBL29064789 0.89 HIF1A (0.68) HIF1ALMNANR3C1SMN1; SMN2CYP2C19
SCHEMBL16020569 0.88 HIF1A (0.78) HIF1ALMNANR3C1SMN1; SMN2CYP2C19
SCHEMBL11814284 0.88 HIF1A (0.81) HIF1ALMNANR3C1SMN1; SMN2CYP2C19
SCHEMBL8538851 0.88 HIF1A (0.69) HIF1ALMNANR3C1SMN1; SMN2CYP2C19
SCHEMBL9789815 0.87 HIF1A (0.66) HIF1ALMNANR3C1SMN1; SMN2CYP2C19
SCHEMBL9437393 0.87 HIF1A (0.75) HIF1ALMNANR3C1SMN1; SMN2CYP2C19
SCHEMBL3108473 0.86 HIF1A (0.69) HIF1ALMNANR3C1SMN1; SMN2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106572970-B Novel gel for topical administration of non-steroidal anti-inflammatory drugs for relief of musculoskeletal pain and method of making same 詹姆斯·布兰查德 2021-04-06 — — CN claimed
WO-2015191402-A1 NOVEL GEL FOR TOPICAL DELIVERY OF NSAIDS TO PROVIDE RELIEF OF MUSCULOSKELETAL PAIN AND METHODS FOR ITS PREPARATION BLANCHARD JAMES (US) 2015-12-17 — — WO claimed
US-9012402-B1 Gel for topical delivery of NSAIDs to provide relief of musculoskeletal pain and methods for its preparation BLANCHARD JAMES (US) 2015-04-21 — — US claimed
US-12636296-B1 Cannabinol analogs and their use as pharmacologically active agents NALU BIO, INC. (US) 2026-05-26 — — US disclosed
US-12605332-B2 Transdermal delivery formulations ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2026-04-21 — — US disclosed
US-12583832-B2 Cannabinoid analogs, formulations, and methods of use NALU BIO, INC. (US) 2026-03-24 — — US disclosed
US-20260001856-A1 CANNABINOID ANALOGS, FORMULATIONS, AND METHODS OF USE NALU BIO, INC. 2026-01-01 — — US disclosed
US-12478576-B2 Transdermal delivery formulations ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2025-11-25 — — US disclosed
US-20250352626-A1 IMMUNE TOLERANCE INDUCTION TO VIRAL CAPSIDS UNIV FLORIDA (US) 2025-11-20 — — US disclosed
US-20250352502-A1 TOPICAL FORMULATIONS OF CYCLOOXYGENASE INHIBITORS AND THEIR USE SMARTECH TOPICAL, INC. (US) 2025-11-20 — — US disclosed
US-20250275988-A1 FORMULATION FOR TREATING URINARY SYSTEM DISORDERS WATERSHED MEDICAL, INC. (US) 2025-09-04 — — US disclosed
US-20030091630-A1 Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data ASSERTIO THERAPEUTICS, INC. 2003-05-15 — — US disclosed
WO-2003035041-A1 GASTRIC RETENTIVE ORAL DOSAGE FORM WITH RESTRICTED DRUG RELEASE IN THE LOWER GASTROINTESTINAL TRACT DEPOMED, INC. (US) 2003-05-01 — — WO disclosed
WO-2003035029-A1 FORMULATION OF AN ERODIBLE, GASTRIC RETENTIVE ORAL DOSAGE FORM USING IN VITRO DISINTEGRATION TEST DATA DEPOMED, INC. (US) 2003-05-01 — — WO disclosed
EP-1239845-A2 HYDROXIDE-RELEASING AGENTS AS SKIN PERMEATION ENHANCERS Dermatrends, Inc. (US) 2002-09-18 — — EP disclosed
US-20020034554-A1 Dual enhancer composition for topical and transdermal drug delivery TECHNOLOGY RECOVERY SYSTEMS, LLC 2002-03-21 — — US disclosed
US-20010051166-A1 Hydroxide-releasing agents as skin permeation enhancers TECHNOLOGY RECOVERY SYSTEMS, LLC 2001-12-13 — — US disclosed
US-20010038861-A1 Transdermal administration of nonsteroidal anti-inflammatory drugs using hydroxide-releasing agents as permeation enhancers TRS II, LLC 2001-11-08 — — US disclosed
WO-2001043775-A2 HYDROXIDE-RELEASING AGENTS AS SKIN PERMEATION ENHANCERS DERMATRENDS, INC. (US) 2001-06-21 — — WO disclosed
US-3956349-A TRIETHYL ORTHOACETATE, ACID CATALYST SYNTEX (U.S.A.) INC. (US) 1976-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020034554-A1 Dual enhancer composition for topical and transdermal drug delivery LIPA, FAAH2, MGLL HIF1A 1727/4885LMNA 2157/4885NR3C1 661/4885
US-12636296-B1 Cannabinol analogs and their use as pharmacologically active agents CNR1, CNR2, OPRL1 HIF1A 894/4885LMNA 750/4885NR3C1 43/4885
US-12605332-B2 Transdermal delivery formulations NOS1, NOS2, VDR HIF1A 685/4885LMNA 3142/4885NR3C1 479/4885
US-20250352626-A1 IMMUNE TOLERANCE INDUCTION TO VIRAL CAPSIDS HAVCR2, MYD88, TLR3 HIF1A 922/4885LMNA 3815/4885NR3C1 1068/4885
US-12583832-B2 Cannabinoid analogs, formulations, and methods of use CNR1, CNR2, CYP8B1 HIF1A 2161/4885LMNA 2505/4885NR3C1 1561/4885
US-20260001856-A1 CANNABINOID ANALOGS, FORMULATIONS, AND METHODS OF USE CNR2, CNR1, CTNND1 HIF1A 4080/4885LMNA 2720/4885NR3C1 3034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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