Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174385 | 0.75 | KDM4E (0.53) | PTGS1PTGS2PIM1PIM3PIK3CD | |
| SCHEMBL8042639 | 0.75 | PIK3CD (0.43) | PIK3CDNOTUMCYP2A6RAB9ANPC1 | |
| SCHEMBL10562949 | 0.74 | ALDH1A1 (0.56) | PTGS1PTGS2PIM1PIM3RAB9A | |
| SCHEMBL9352473 | 0.73 | PTGS2 (0.57) | PTGS1PTGS2RAB9ANPC1MEN1 | |
| SCHEMBL17589831 | 0.69 | NPC1 (0.44) | PIK3CDNOTUMCYP2A6RAB9ANPC1 | |
| SCHEMBL9479043 | 0.69 | SNCA (0.68) | PTGS1PTGS2PIM1PIM3MAPT | |
| SCHEMBL8157379 | 0.68 | PIM1 (0.53) | PTGS1PTGS2PIM1PIM3RAB9A | |
| SCHEMBL1662273 | 0.67 | PIK3CD (0.73) | PIK3CDNOTUMCYP2A6RAB9ANPC1 | |
| SCHEMBL1594532 | 0.67 | PTGS1 (0.43) | PTGS1PTGS2PIM1PIM3 | |
| SCHEMBL1594907 | 0.67 | CDK2 (0.44) | PTGS1PTGS2PIM1PIM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780392-A | Heterocyclyl-1,3,4-thiadiazolyloxyacetamides and their use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0755395-A1 | HETEROCYCLYL-1,3,4-THIADIAZOLYLOXYACETAMIDES | BAYER AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995027711-A1 | HETEROCYCLYL-1,3,4-THIADIAZOLYLOXYACETAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-19 | — | — | WO | disclosed |