SCHEMBL8539148

SCHEMBL8539148

COC(=O)c1ccc(NN)cc1S(N)(=O)=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.59
CA1 P00915 5/20 0.59
CA9 Q16790 5/20 0.59
CA5A P35218 2/20 0.59
GAA P10253 3/20 0.49
CDK1 P06493 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
CA12 O43570 4/20 0.44
CA14 Q9ULX7 4/20 0.44
CA7 P43166 3/20 0.44
PDK2 Q15119 1/20 0.44
PDK4 Q16654 1/20 0.44
KDM4E B2RXH2 3/20 0.41
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9530711 0.85 CA1 (0.50) CA2CA1CA9CA5ACA12
SCHEMBL8539913 0.84 CA2 (0.55) CA2CA1CA9CA5AGAA
SCHEMBL7953153 0.82 CA1 (0.43) CA2CA1CA9CA5AGAA
SCHEMBL27453911 0.82 CA2 (0.54) CA2CA1CA9CA5AGAA
SCHEMBL27452999 0.82 CA2 (0.54) CA2CA1CA9CA5AGAA
SCHEMBL8030650 0.82 GAA (0.67) CA2CA1CA9CA5AGAA
SCHEMBL8662947 0.81 CA2 (0.52) CA2CA1CA9CA5AGAA
SCHEMBL11372105 0.81 CA1 (0.63) CA2CA1CA9CA5AGAA
SCHEMBL22010624 0.81 CA2 (0.63) CA2CA1CA9CA5AGAA
SCHEMBL8536174 0.80 CA2 (0.51) CA2CA1CA9CA5AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0562575-B1 N-substituted-3-(substituted hydrazino)-benzenesulfonamide derivative, preparation process thereof, and herbicidal compositions KUREHA CHEMICAL IND CO LTD (JP) 1998-09-16 EP disclosed
EP-0382437-B1 N-substituted-3-(substituded hydrazino)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA CHEMICAL IND CO LTD (JP) 1995-08-16 EP disclosed
EP-0382436-B1 N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA CHEMICAL IND CO LTD (JP) 1995-05-10 EP disclosed
US-5362885-A Herbicides KUREHA KAGAKU KOGYO K.K. (JP) 1994-11-08 US disclosed
EP-0562575-A2 N-substituted-3-(substited hydrazino)-benzenesulfonamide derivatives, prepation process thereof, and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-09-29 EP disclosed
US-5242894-A N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, and herbicidal compositions KUREHA KAGAKU KOGYO K.K. (JP) 1993-09-07 US disclosed
US-5198566-A N-substituted-3-(substituted hydrazino)-benzenesulfonamides KUREHA KAGAKU KOGYO K.K. (JP) 1993-03-30 US disclosed
US-5151114-A Applying to weeds ARAHORI HIDEO (JP) 1992-09-29 US disclosed
US-5127937-A N-SUBSTITUTED-3-(NITROGEN-CONTAINING 5-MEMBERED RING)-BENZENESULFONAMIDE DERIVATIVES, AND HERBICIDAL COMPOSITIONS KUREHA KAGAKU KOGYO K.K. (JP) 1992-07-07 US disclosed
US-5059238-A Controlling mono- and dicotyledons KUREHA KAGAKU KOGYO K.K. (JP) 1991-10-22 US disclosed
EP-0382437-A1 N-substituted-3-(substituded hydrazino)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-16 EP disclosed
EP-0382436-A1 N-substituted-3-(nitrogen-containing 5-membered ring)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-16 EP disclosed