Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201412 | 0.87 | CDK1 (0.43) | CA1CA2CA5ACA9CDK1 | |
| SCHEMBL8661923 | 0.87 | CDK1 (0.43) | CA1CA2CA5ACA9CDK1 | |
| SCHEMBL7952829 | 0.86 | MAPT (0.46) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL8661476 | 0.84 | CDK1 (0.45) | CA1CA2CA5ACA9CDK1 | |
| SCHEMBL7875914 | 0.83 | GAA (0.54) | CA1CA2CA5ACA9CDK1 | |
| SCHEMBL8539148 | 0.82 | CA2 (0.59) | CA1CA2CA5ACA9CDK1 | |
| SCHEMBL6151581 | 0.81 | KDM4E (0.52) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL7924986 | 0.81 | LMNA (0.45) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL7924819 | 0.81 | KDM4E (0.44) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL29295507 | 0.80 | NR4A2 (0.43) | CA1CA2CA5ACA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265348-B1 | Alkylidenehydrazinophenylsulfonylureas, processes for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| US-5922645-A | PRE-EMERGENCE AND POST-EMERGENCE HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5849666-A | N-substituted hydrazinophenylsulfonylureas, processes for their preparation and their use as herbicides and plant growth regulations | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-15 | — | — | US | disclosed |