Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539224 | 1.00 | MEN1 (0.47) | MEN1KMT2AL3MBTL1ATMLMNA | |
| SCHEMBL15076440 | 0.88 | MCHR1 (0.43) | MEN1KMT2ALMNABCHEACHE | |
| SCHEMBL4522120 | 0.85 | SIGMAR1 (0.46) | MEN1KMT2ALMNAALDH1A1BCHE | |
| SCHEMBL4522126 | 0.85 | SIGMAR1 (0.46) | MEN1KMT2ALMNAALDH1A1BCHE | |
| SCHEMBL31397226 | 0.85 | ACHE (0.44) | MEN1KMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL4579407 | 0.80 | KMT2A (0.56) | MEN1KMT2ALMNAMAPTADORA1 | |
| Hydrochloric Acid SCHEMBL9538926 | 0.79 | MEN1 (0.55) | MEN1KMT2ALMNAMAPTADORA1 | |
| SCHEMBL8576896 | 0.78 | MEN1 (0.54) | MEN1KMT2ALMNAMAPTADORA1 | |
| SCHEMBL2831248 | 0.78 | MEN1 (0.54) | MEN1KMT2ALMNAMAPTADORA1 | |
| SCHEMBL2831250 | 0.78 | MEN1 (0.54) | MEN1KMT2ALMNAMAPTADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |