Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536322 | 0.86 | MAOB (0.44) | ALKBH3MAOBLMNAALDH1A1HPGD | |
| SCHEMBL28530317 | 0.80 | ALKBH3 (0.52) | ALKBH3MAOBSYKLMNAALDH1A1 | |
| SCHEMBL10372894 | 0.77 | ALKBH3 (0.50) | ALKBH3MAOBSYKLMNAALDH1A1 | |
| SCHEMBL8537635 | 0.72 | MAOB (0.47) | ALKBH3MAOBLMNAALDH1A1HPGD | |
| SCHEMBL8538998 | 0.72 | GSTP1 (0.51) | MAOBHPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28906223 | 0.71 | ACHE (0.37) | ALKBH3MAOBLMNAALDH1A1HPGD | |
| SCHEMBL28528548 | 0.71 | CA1 (0.35) | LMNAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL29233386 | 0.69 | ACHE (0.50) | ALKBH3MAOBSYKLMNAALDH1A1 | |
| SCHEMBL8539308 | 0.68 | TDP1 (0.49) | LMNAALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL13932512 | 0.68 | ACHE (0.54) | ALKBH3MAOBSYKLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |