Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537772 | 0.90 | ALDH1A1 (0.47) | KDM4EALDH1A1HTTGAATSHR | |
| SCHEMBL8539779 | 0.82 | KDM4E (0.60) | KDM4EPOLBALDH1A1HTTGAA | |
| SCHEMBL8543060 | 0.82 | ADAM17 (0.45) | KDM4EALDH1A1SMN1; SMN2HPGDOPRK1 | |
| SCHEMBL8540442 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2OPRK1OPRM1OPRD1 | |
| SCHEMBL8542198 | 0.79 | KDM4E (0.57) | KDM4EPOLBALDH1A1HTTGAA | |
| SCHEMBL8539612 | 0.77 | KDM4E (0.78) | KDM4EPOLBALDH1A1HTTGAA | |
| SCHEMBL8543401 | 0.76 | USP2 (0.47) | KDM4EPOLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28508997 | 0.76 | ALDH1A1 (0.72) | KDM4EALDH1A1HTTGAATSHR | |
| SCHEMBL28503664 | 0.76 | ALDH1A1 (0.72) | KDM4EALDH1A1HTTGAATSHR | |
| SCHEMBL29683884 | 0.76 | ALDH1A1 (0.72) | KDM4EALDH1A1HTTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | claimed |