Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CFB | P00751 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539332 | 0.90 | KDM4E (0.53) | ALDH1A1KDM4EGAATSHRHTT | |
| SCHEMBL8543060 | 0.83 | ADAM17 (0.45) | ALDH1A1KDM4ESMN1; SMN2ADAM17OPRK1 | |
| SCHEMBL8540442 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2ADAM17OPRK1OPRM1 | |
| SCHEMBL8541053 | 0.80 | CYP3A4 (0.47) | ALDH1A1HTTCYP3A4CYP2C9KMT2A | |
| SCHEMBL9250795 | 0.80 | OPRK1 (0.47) | ALDH1A1KDM4EGAATSHRHTT | |
| SCHEMBL8540467 | 0.79 | KDM4E (0.52) | ALDH1A1KDM4EGAATSHRHTT | |
| SCHEMBL8543401 | 0.78 | USP2 (0.47) | ALDH1A1KDM4EHTTSMN1; SMN2ADAM17 | |
| SCHEMBL8539128 | 0.76 | POLB (0.46) | ALDH1A1HTTSMN1; SMN2ADAM17CYP3A4 | |
| SCHEMBL8538305 | 0.76 | OPRK1 (0.48) | ALDH1A1KDM4EGAATSHRHTT | |
| SCHEMBL8539767 | 0.76 | ALDH1A1 (0.46) | ALDH1A1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | claimed |
| EP-0671388-A1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-09-13 | — | — | EP | claimed |