SCHEMBL8539438

SCHEMBL8539438

CC1CCC(C(C)C)C(c2ccc(Oc3cccc(N)c3)cc2)(c2ccccc2Oc2cccc(N)c2)C1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.39
ALDH1A1 P00352 4/20 0.33
ATM Q13315 1/20 0.32
LTA4H P09960 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
GAA P10253 2/20 0.32
MEN1 O00255 1/20 0.32
MITF O75030 1/20 0.32
MAPT P10636 1/20 0.32
GFER P55789 1/20 0.32
KMT2A Q03164 1/20 0.32
NLRP1 Q9C000 1/20 0.32
NOD2 Q9HC29 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8588841 0.92 MAOB (0.38) MAOBALDH1A1ATMGAAMAPT
SCHEMBL8698975 0.91 NCOA1 (0.36) ALDH1A1
SCHEMBL8588502 0.90 MAOB (0.42) MAOBALDH1A1ATMLTA4HSMN1; SMN2
SCHEMBL8196760 0.84 NCOA1 (0.39) ALDH1A1
SCHEMBL8536449 0.81 ALDH1A1 (0.31) ALDH1A1
SCHEMBL8196761 0.78 ALDH1A1 (0.38) MAOBALDH1A1SMN1; SMN2GAAMEN1
SCHEMBL8590130 0.69
SCHEMBL8697608 0.68 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2MAPT
SCHEMBL9348587 0.68 MAOB (0.50) MAOBALDH1A1ATMLTA4HSMN1; SMN2
SCHEMBL6290463 0.67 MAOB (0.77) MAOBALDH1A1ATMLTA4HSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750789-A FROM CORRESPONDING DIAMINE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-05-12 US claimed
US-5750789-A FROM CORRESPONDING DIAMINE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-05-12 US disclosed
US-5734008-A AROMATIC ETHERDIAMINES FOR POLYIMIDE FILMS FOR PRINTED CIRCUITS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-03-31 US disclosed