Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 5/20 | 0.44 |
| ▸ | PYGM | P11217 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226205 | 0.83 | LMNA (0.50) | TK2PYGMLMNASMN1; SMN2P2RY6 | |
| SCHEMBL9226210 | 0.83 | LMNA (0.50) | TK2PYGMLMNASMN1; SMN2P2RY6 | |
| SCHEMBL7811414 | 0.82 | P2RY6 (0.54) | PYGMLMNASMN1; SMN2P2RY6P2RY14 | |
| SCHEMBL9029499 | 0.82 | P2RY2 (0.51) | TK2PYGMP2RY2 | |
| SCHEMBL9030185 | 0.82 | P2RY2 (0.51) | TK2PYGMP2RY2 | |
| SCHEMBL10643570 | 0.79 | TK2 (0.45) | TK2 | |
| SCHEMBL10647357 | 0.79 | TK2 (0.45) | TK2 | |
| SCHEMBL10642490 | 0.79 | DNPH1 (0.40) | TK2P2RY6P2RY14NT5EP2RY2 | |
| SCHEMBL10646803 | 0.79 | DNPH1 (0.40) | TK2P2RY6P2RY14NT5EP2RY2 | |
| SCHEMBL10644559 | 0.78 | TK2 (0.37) | TK2P2RY6P2RY14NT5EP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851866-A1 | THERAPEUTIC COMPOUNDS | Oxford GlycoSciences (UK) Limited (GB) | 1998-07-08 | — | — | EP | disclosed |
| WO-1997000882-A1 | THERAPEUTIC COMPOUNDS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 1997-01-09 | — | — | WO | disclosed |