Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.62 |
| ▸ | MGLL | Q99685 | 3/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752149 | 0.87 | MGLL (0.75) | FFAR1MGLLLTA4H | |
| SCHEMBL1172031 | 0.86 | MGLL (0.73) | FFAR1MGLLLTA4H | |
| SCHEMBL1171728 | 0.86 | MGLL (0.73) | FFAR1MGLLLTA4H | |
| SCHEMBL8577180 | 0.85 | MGLL (0.72) | FFAR1MGLLLTA4H | |
| SCHEMBL8499096 | 0.85 | S1PR1 (0.69) | S1PR1S1PR3S1PR5PLA2G4B | |
| SCHEMBL15270887 | 0.85 | S1PR1 (0.69) | S1PR1S1PR3S1PR5PLA2G4B | |
| SCHEMBL8497102 | 0.85 | S1PR1 (0.69) | S1PR1S1PR3S1PR5PLA2G4B | |
| SCHEMBL2686941 | 0.84 | S1PR1 (0.67) | S1PR1S1PR3S1PR5PLA2G4B | |
| SCHEMBL9393649 | 0.83 | S1PR1 (0.66) | S1PR1S1PR3S1PR5PLA2G4B | |
| SCHEMBL9452163 | 0.83 | S1PR1 (0.66) | S1PR1S1PR3S1PR5PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |