Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.72 |
| ▸ | LTA4H | P09960 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752149 | 0.99 | MGLL (0.75) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL1172031 | 0.97 | MGLL (0.73) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL1171728 | 0.97 | MGLL (0.73) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL8855387 | 0.88 | FFAR1 (0.60) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL4026021 | 0.88 | MGLL (0.58) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL15482174 | 0.86 | MGLL (0.66) | MGLLLTA4HEPHX2LMNACYP1A2 | |
| SCHEMBL6750228 | 0.86 | MGLL (0.74) | MGLLBCHEFFAR1 | |
| SCHEMBL8539748 | 0.85 | FFAR1 (0.62) | MGLLLTA4HFFAR1 | |
| SCHEMBL8577307 | 0.85 | MGLL (0.76) | MGLLBCHEFFAR1 | |
| SCHEMBL1171851 | 0.84 | MGLL (1.00) | MGLLLTA4HEPHX2BCHEFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912562-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003505-A2 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |