Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.75 |
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171728 | 0.99 | MGLL (0.73) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL1172031 | 0.99 | MGLL (0.73) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL8577180 | 0.99 | MGLL (0.72) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL8539748 | 0.87 | FFAR1 (0.62) | MGLLLTA4HFFAR1 | |
| SCHEMBL8855387 | 0.87 | FFAR1 (0.60) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL4026021 | 0.87 | MGLL (0.58) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL8577307 | 0.86 | MGLL (0.76) | MGLLBCHEFFAR1 | |
| SCHEMBL1172045 | 0.86 | MGLL (0.75) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL1171851 | 0.86 | MGLL (1.00) | MGLLLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL1172242 | 0.86 | MGLL (1.00) | MGLLLTA4HEPHX2BCHEFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053972-A1 | Medicinal compositions having improved absorbability | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1350793-A1 | MEDICINAL COMPOSITIONS HAVING IMPROVED ABSORBABILITY | Takeda Chemical Industries, Ltd. (JP) | 2003-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053972-A1 | Medicinal compositions having improved absorbability | EGFR, ERBB2, ERBB3 | MGLL 490/4885LTA4H 1860/4885EPHX2 3048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.