Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543486 | 0.77 | CA12 (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8540729 | 0.77 | CA1 (0.31) | CA12CA1CA2CA9 | |
| SCHEMBL21135673 | 0.65 | CA2 (0.35) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28845208 | 0.63 | CYP1A2 (0.34) | — | |
| SCHEMBL11672291 | 0.62 | KDM4E (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9427142 | 0.62 | CA9 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14694011 | 0.62 | SMN1; SMN2 (0.37) | LMNA | |
| SCHEMBL20000078 | 0.62 | ALDH1A1 (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1131655 | 0.61 | CA12 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14324822 | 0.61 | CA1 (0.52) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584085-B1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5554606-A | THIENAMYCIN DERIVATIVES; PSEUDOMONAS | ZENECA LIMITED (GB) | 1996-09-10 | — | — | US | disclosed |
| EP-0584085-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992017479-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD. (GB) | 1992-10-15 | — | — | WO | disclosed |