Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539826 | 0.88 | EGLN1 (0.30) | — | |
| SCHEMBL8542335 | 0.88 | EGLN1 (0.37) | DDR1GSTO1 | |
| SCHEMBL8538459 | 0.87 | AKR1C3 (0.33) | AKR1C3AKR1C2DDR1GSTO1CTSS | |
| SCHEMBL8538275 | 0.84 | PSEN1 (0.30) | — | |
| SCHEMBL8541620 | 0.83 | DDR1 (0.39) | DDR1 | |
| SCHEMBL8541505 | 0.82 | DDR1 (0.32) | DDR1GSTO1 | |
| SCHEMBL6935396 | 0.82 | SLC9A1 (0.38) | — | |
| SCHEMBL8542924 | 0.80 | EGLN1 (0.40) | DDR1 | |
| SCHEMBL8543032 | 0.80 | SLC9A1 (0.33) | — | |
| SCHEMBL8538912 | 0.78 | CCR2 (0.34) | DDR1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071743-C | Sulfuryl or sulfinyl benzoyl guanidine derivative | MERCK PATENT GMBH (DE) | 2001-09-26 | — | — | CN | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| CN-1148590-A | Sulfuryl or sulfinyl benzoyl guanidine derivative | MERCK PATENT GMBH (DE) | 1997-04-30 | — | — | CN | disclosed |