Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 3/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 2/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541620 | 0.87 | DDR1 (0.39) | DDR1CCR2 | |
| SCHEMBL8542335 | 0.83 | EGLN1 (0.37) | DDR1GSTO1 | |
| SCHEMBL8542924 | 0.83 | EGLN1 (0.40) | DDR1CCR2 | |
| SCHEMBL8536966 | 0.82 | CNR2 (0.32) | GSTO1CNR2ALOX15CA12CA1 | |
| SCHEMBL8539798 | 0.82 | AKR1C3 (0.32) | DDR1GSTO1 | |
| SCHEMBL8539830 | 0.81 | THRB (0.37) | DDR1CNR2CCR2 | |
| SCHEMBL8539826 | 0.81 | EGLN1 (0.30) | — | |
| SCHEMBL8538912 | 0.81 | CCR2 (0.34) | DDR1CNR2CA12CA1CA2 | |
| SCHEMBL8543319 | 0.80 | HSD11B1 (0.41) | CA12CA1CA2CA4CA6 | |
| SCHEMBL8537724 | 0.80 | THRB (0.41) | CNR2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5782934-A | Process of dyeing with disazo dyes containing a fluorosulphonyl group and use thereof | ZENECA LIMITED (GB) | 1998-07-21 | — | — | US | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |