Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.53 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536577 | 0.94 | TK1 (0.61) | TK1XDHCTSL | |
| SCHEMBL8589183 | 0.91 | TK1 (0.54) | TK1XDHCTSL | |
| SCHEMBL8538454 | 0.91 | TK1 (0.54) | TK1 | |
| SCHEMBL8535784 | 0.85 | TK1 (0.65) | TK1 | |
| SCHEMBL8535178 | 0.85 | XDH (0.45) | TK1XDHGPR84 | |
| SCHEMBL5179771 | 0.84 | MEN1 (0.61) | TK1XDHGPR84 | |
| SCHEMBL16197990 | 0.79 | TK1 (0.54) | TK1 | |
| SCHEMBL8536573 | 0.78 | XDH (0.47) | XDHGPR84 | |
| SCHEMBL10047154 | 0.78 | XDH (0.40) | XDH | |
| SCHEMBL16020718 | 0.77 | POLB (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | disclosed |