Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | ADA | P00813 | 5/20 | 0.38 |
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22571149 | 0.79 | ADA (0.51) | XDHCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL8535178 | 0.79 | XDH (0.45) | XDHGPR84 | |
| SCHEMBL8539824 | 0.78 | TK1 (0.53) | XDHGPR84 | |
| SCHEMBL8589183 | 0.78 | TK1 (0.54) | XDH | |
| SCHEMBL7815960 | 0.77 | HPRT1 (0.54) | XDHCYP3A4ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8536577 | 0.77 | TK1 (0.61) | XDH | |
| SCHEMBL21011178 | 0.76 | HPRT1 (0.38) | XDHADAPDE2ACYP3A4PDE4A | |
| SCHEMBL5179771 | 0.74 | MEN1 (0.61) | XDHGPR84CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL25979404 | 0.72 | CDK1 (0.41) | CCNB2CDK1CCNB1CCNB3PDE2A | |
| SCHEMBL14624652 | 0.71 | CDK2 (0.36) | CDK1CCNB1CYP3A4ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | disclosed |