Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8539839

N=C(N)c1ccc(N2CCN(CC(=O)NCCC(=O)O)C2=O)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 19/20 0.50
ITGA2B P08514 19/20 0.50
ITGB2 P05107 1/20 0.49
ITGAM P11215 1/20 0.49
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7405707 0.94 ITGB3 (0.55) ITGB3ITGA2BITGB2ITGAM
SCHEMBL7395840 0.88 ITGB3 (0.50) ITGB3ITGA2B
SCHEMBL7397288 0.88 ITGB3 (0.53) ITGB3ITGA2B
SCHEMBL9052848 0.85 ITGB3 (0.55) ITGB3ITGA2B
SCHEMBL7399049 0.82 ITGB3 (0.48) ITGB3ITGA2B
SCHEMBL7398279 0.80 ITGB3 (0.62) ITGB3ITGA2B
SCHEMBL7401407 0.79 ITGB3 (0.50) ITGB3ITGA2B
SCHEMBL7402530 0.79 LMNA (0.46) ITGB3ITGA2B
Hydrochloric Acid SCHEMBL7404001 0.78 F10 (0.51) ITGB3ITGA2B
SCHEMBL7402213 0.78 ITGB3 (0.43) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0715623-B1 PLATELET AGGREGATION INHIBITORS SEARLE & CO (US) 1998-09-09 EP claimed