Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628923 | 0.89 | KMT2A (0.56) | KMT2AHTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL7756307 | 0.79 | POLB (0.50) | KMT2AHTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL8536459 | 0.78 | SRC (0.43) | POLBL3MBTL1SMN1; SMN2LMNASRC | |
| SCHEMBL6950812 | 0.78 | SRC (0.43) | KMT2AHTTL3MBTL1PTGS1PTGS2 | |
| SCHEMBL306964 | 0.77 | CA1 (0.54) | KMT2AHTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL29386813 | 0.77 | CA1 (0.54) | KMT2AHTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL8825702 | 0.76 | L3MBTL1 (0.47) | KMT2AHTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL8473051 | 0.76 | PTGS2 (0.64) | KMT2AHTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL6400516 | 0.76 | KMT2A (0.55) | KMT2AHTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL503435 | 0.76 | KMT2A (0.55) | KMT2AHTTPOLBNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |