Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814300 | 0.90 | CUL4A (0.46) | HDAC1HDAC6CUL4ANCEH1SLC1A3 | |
| SCHEMBL8540923 | 0.82 | HDAC1 (0.35) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL28791805 | 0.80 | HDAC1 (0.35) | HDAC1HDAC6PKMNCEH1CA1 | |
| SCHEMBL8370837 | 0.78 | NPC1 (0.37) | HDAC1HDAC6CUL4APOLBL3MBTL1 | |
| SCHEMBL3708440 | 0.75 | POLB (0.52) | PKMPOLBL3MBTL1NPC1 | |
| SCHEMBL17796987 | 0.73 | SLC1A3 (0.38) | PKMNCEH1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7211056 | 0.73 | KDM4E (0.40) | HDAC1HDAC6CUL4AL3MBTL1RAB9A | |
| SCHEMBL9444974 | 0.73 | TDP1 (0.40) | PKMPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL2681143 | 0.72 | PDE2A (0.34) | POLBL3MBTL1ALDH1A1 | |
| SCHEMBL2916569 | 0.71 | AKR1B1 (0.35) | CUL4APKMCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659735-B1 | PROCESS FOR PRODUCING ANILINE DERIVATIVE | SAGAMI CHEM RES (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5639915-A | Process for the production of aniline derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0659735-A1 | PROCESS FOR PRODUCING ANILINE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-06-28 | — | — | EP | disclosed |