Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211056 | 0.89 | KDM4E (0.40) | HDAC1HDAC6CYP4F2CYP4A11KDM4E | |
| SCHEMBL28688972 | 0.86 | MEN1 (0.36) | HDAC1HDAC6CYP4F2CYP4A11KDM4E | |
| SCHEMBL8370837 | 0.82 | NPC1 (0.37) | HDAC1HDAC6ALDH1A1RAB9A | |
| SCHEMBL8539890 | 0.82 | HDAC1 (0.36) | HDAC1HDAC6CYP4F2CYP4A11KDM4E | |
| SCHEMBL29286693 | 0.76 | POLB (0.36) | HDAC1HDAC6KDM4EHTT | |
| SCHEMBL2916569 | 0.75 | AKR1B1 (0.35) | CYP4F2CYP4A11LMNAMAPK1HTT | |
| SCHEMBL6430813 | 0.74 | KDM4E (0.38) | HDAC1HDAC6KDM4EALDH1A1LMNA | |
| SCHEMBL9814300 | 0.73 | CUL4A (0.46) | HDAC1HDAC6KDM4EALDH1A1LMNA | |
| SCHEMBL8084592 | 0.73 | CUL4A (0.46) | KDM4EALDH1A1LMNAHTTRAB9A | |
| SCHEMBL2572461 | 0.72 | TAAR1 (0.37) | KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659735-B1 | PROCESS FOR PRODUCING ANILINE DERIVATIVE | SAGAMI CHEM RES (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5639915-A | Process for the production of aniline derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0659735-A1 | PROCESS FOR PRODUCING ANILINE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-06-28 | — | — | EP | disclosed |