SCHEMBL8540010

SCHEMBL8540010

CC(=O)Nc1ccc(O)c(CN(CC(=O)O)CC(=O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.47
PKM P14618 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 2/20 0.43
CA12 O43570 1/20 0.43
BRD4 O60885 1/20 0.43
NR1I2 O75469 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MB P02144 1/20 0.43
CYP1A1 P04798 1/20 0.43
CA3 P07451 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
RARG P13631 1/20 0.43
TSHR P16473 1/20 0.43
ALOX5AP P20292 1/20 0.43
CA4 P22748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15094312 0.86 POLB (0.63) POLBPKMSMN1; SMN2MEN1KMT2A
SCHEMBL30230771 0.86 POLB (0.63) POLBPKMSMN1; SMN2MEN1KMT2A
SCHEMBL8541736 0.84 LMNA (0.46) POLBSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL28627643 0.83 EGFR (0.57) POLBPKMSMN1; SMN2MEN1KMT2A
SCHEMBL28837437 0.83 POLB (0.50) POLBPKMSMN1; SMN2MEN1KMT2A
SCHEMBL20536628 0.81 POLB (0.43) POLBPKMSMN1; SMN2MEN1KMT2A
SCHEMBL31198180 0.80 POLB (0.58) POLBPKMSMN1; SMN2MEN1KMT2A
SCHEMBL9773576 0.80 POLB (0.50) POLBPKMSMN1; SMN2MEN1KMT2A
SCHEMBL8995416 0.79 LMNA (0.41) MEN1KMT2AALDH1A1CA12BRD4
SCHEMBL8674450 0.79 LMNA (0.41) MEN1KMT2AALDH1A1CA12BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150024123-A1 CATALYSTS FOR ELECTROLESS METALLIZATION CONTAINING IMINODIACETIC ACID AND DERIVATIVES ROHM AND HAAS ELECTRONIC MATERIALS LLC 2015-01-22 US claimed
EP-2826562-A2 Catalysts for electroless metallization containing iminodiacetic acid and derivatives Rohm and Haas Electronic Materials LLC (US) 2015-01-21 EP claimed
EP-0367223-A2 Chelants possessing ortho ligating functionality and complexes thereof THE DOW CHEMICAL COMPANY (US) 1990-05-09 EP claimed
EP-2826562-A2 Catalysts for electroless metallization containing iminodiacetic acid and derivatives Rohm and Haas Electronic Materials LLC (US) 2015-01-21 EP disclosed
EP-0497356-B1 Compositions and method for soft tissue tumors DOW CHEMICAL CO (US) 1998-08-12 EP disclosed
US-5714631-A FOR DELIVERING THERAPEUTIC RADIATION DOSES TO CALCIFIC TUMORS AND METASTATIC BONE CANCER THE DOW CHEMICAL COMPANY (US) 1998-02-03 US disclosed
US-5696239-A BINDING TO ANTIBODIES; DIAGNOSIS, THERAPY TUMORS; RELIEF OFBONE PAIN THE DOW CHEMICAL COMPANY (US) 1997-12-09 US disclosed
EP-0566166-B1 Chelants possessing ortho ligating functionality and complexes thereof DOW CHEMICAL CO (US) 1996-09-25 EP disclosed
EP-0570022-B1 Chelants possessing ortho ligating functionality and complexes thereof DOW CHEMICAL CO (US) 1996-07-31 EP disclosed
US-5342925-A A metal-phenolic carboxylate ligand complex; ligand to metal ratio at least 20:1 THE DOW CHEMICAL COMPANY (US) 1994-08-30 US disclosed
US-5342604-A Bone disorders THE DOW CHEMICAL COMPANY (US) 1994-08-30 US disclosed
EP-0570022-A2 Chelants possessing ortho ligating functionality and complexes thereof THE DOW CHEMICAL COMPANY (US) 1993-11-18 EP disclosed
EP-0566166-A1 Chelants possessing ortho ligating functionality and complexes thereof THE DOW CHEMICAL COMPANY (a Delaware corporation) (US) 1993-10-20 EP disclosed
WO-1992013826-A1 COMPOSITIONS AND METHOD FOR SOFT TISSUE TUMORS THE DOW CHEMICAL COMPANY (US) 1992-08-20 WO disclosed
EP-0497356-A1 Compositions and method for soft tissue tumors THE DOW CHEMICAL COMPANY (US) 1992-08-05 EP disclosed
EP-0367223-A2 Chelants possessing ortho ligating functionality and complexes thereof THE DOW CHEMICAL COMPANY (US) 1990-05-09 EP disclosed