Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674450 | 1.00 | LMNA (0.41) | LMNATDP1EYA2APPACE | |
| SCHEMBL8541736 | 0.94 | LMNA (0.46) | LMNATDP1ALDH1A1GAATSHR | |
| SCHEMBL8995401 | 0.83 | GAA (0.41) | LMNATDP1ALDH1A1GAATSHR | |
| SCHEMBL8995403 | 0.80 | GAA (0.36) | LMNATDP1EYA2APPACE | |
| SCHEMBL8540010 | 0.79 | POLB (0.47) | ALDH1A1GAATSHRKDM4ECA1 | |
| SCHEMBL8832295 | 0.79 | TDP1 (0.48) | LMNATDP1EYA2APPACE | |
| SCHEMBL12749593 | 0.74 | TDP1 (0.38) | LMNATDP1EYA2APPACE | |
| SCHEMBL10809043 | 0.73 | ALDH1A1 (0.46) | LMNATDP1EYA2APPACE | |
| SCHEMBL21908843 | 0.72 | POLB (0.46) | LMNATDP1ALDH1A1GAAKDM4E | |
| SCHEMBL5265431 | 0.72 | EGFR (0.43) | LMNATDP1EYA2APPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566166-B1 | Chelants possessing ortho ligating functionality and complexes thereof | DOW CHEMICAL CO (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0570022-B1 | Chelants possessing ortho ligating functionality and complexes thereof | DOW CHEMICAL CO (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0570022-A2 | Chelants possessing ortho ligating functionality and complexes thereof | THE DOW CHEMICAL COMPANY (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0566166-A1 | Chelants possessing ortho ligating functionality and complexes thereof | THE DOW CHEMICAL COMPANY (a Delaware corporation) (US) | 1993-10-20 | — | — | EP | disclosed |