Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497225 | 0.96 | HIF1A (0.40) | HIF1AALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL7494938 | 0.87 | HIF1A (0.49) | HIF1AALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL17949971 | 0.85 | HIF1A (0.45) | HIF1AALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7495777 | 0.85 | HIF1A (0.44) | HIF1AKMT2AMEN1LMNA | |
| SCHEMBL7498528 | 0.82 | HIF1A (0.39) | HIF1AKCNH2 | |
| SCHEMBL8540309 | 0.82 | ALDH1A1 (0.36) | ALDH1A1HTTKMT2AMEN1MAPT | |
| SCHEMBL7492706 | 0.82 | HIF1A (0.42) | HIF1AKMT2AMEN1EPHX2 | |
| SCHEMBL7716053 | 0.81 | HIF1A (0.48) | HIF1AALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL17937973 | 0.81 | HIF1A (0.48) | HIF1AALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL7716055 | 0.81 | HIF1A (0.48) | HIF1AALDH1A1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |