Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374103 | 0.85 | CREB1 (0.48) | TERTPRKDCPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL7371500 | 0.82 | ADAMTS4 (0.42) | ACHEMAOBTERTDHODHADAMTS4 | |
| SCHEMBL6963290 | 0.82 | TERT (0.43) | TERTDHODHADAMTS4PRKAB2PRKAG1 | |
| SCHEMBL7376620 | 0.81 | ADAMTS4 (0.42) | ACHETERTDHODHADAMTS4GRM2 | |
| SCHEMBL7371871 | 0.81 | ADAMTS4 (0.41) | TERTDHODHADAMTS4ACACBGRM2 | |
| SCHEMBL8438712 | 0.80 | ADAMTS4 (0.45) | TERTDHODHADAMTS4ACACBPRKAB2 | |
| SCHEMBL7375817 | 0.79 | MEN1 (0.41) | TERTDHODHADAMTS4ACACBGRM2 | |
| SCHEMBL6959848 | 0.79 | ADAMTS4 (0.40) | ACHEMAOBTERTDHODHADAMTS4 | |
| SCHEMBL7379170 | 0.79 | DHODH (0.39) | ACHEMAOBTERTDHODHADAMTS4 | |
| SCHEMBL7375137 | 0.79 | ADAMTS4 (0.43) | TERTADAMTS4ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |