SCHEMBL8540385

SCHEMBL8540385

CCN(CC)Nc1ccc(N)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 4/20 0.46
TDP1 Q9NUW8 4/20 0.46
TSHR P16473 3/20 0.46
MAPK1 P28482 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
GFER P55789 2/20 0.46
PSMD14 O00487 1/20 0.46
RECQL P46063 1/20 0.46
MAPT P10636 5/20 0.38
CYP2C19 P33261 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
ALOX12 P18054 1/20 0.38
HTT P42858 1/20 0.38
NR4A1 P22736 1/20 0.38
RAB9A P51151 2/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28800426 0.98 ALDH1A1 (0.45) ALDH1A1CYP3A4TDP1TSHRMAPK1
Hydrochloric Acid SCHEMBL10901283 0.98 ALDH1A1 (0.45) ALDH1A1CYP3A4TDP1TSHRMAPK1
SCHEMBL9594102 0.81 HRH3 (0.39) ALDH1A1CYP3A4TDP1TSHRL3MBTL1
SCHEMBL7655941 0.79 MAPT (0.47) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1
SCHEMBL2411167 0.79 MAPT (0.46) ALDH1A1TDP1TSHRMAPK1L3MBTL1
SCHEMBL6256672 0.78 MAPT (0.44) ALDH1A1CYP3A4TDP1TSHRMAPK1
SCHEMBL27850554 0.77 SIGMAR1 (0.36) L3MBTL1CYP1A2PMP22KDM4ECYP2D6
SCHEMBL50189 0.76 L3MBTL1 (0.52) ALDH1A1TDP1TSHRMAPK1L3MBTL1
SCHEMBL27822621 0.75 ALDH1A1 (0.41) ALDH1A1CYP3A4TDP1TSHRMAPK1
Hydrochloric Acid SCHEMBL11760188 0.74 L3MBTL1 (0.50) ALDH1A1TDP1TSHRMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101720307-B Treatment of water with hypobromite solution CHRIST WATER TECHNOLOGY AG 2012-12-12 CN disclosed
CN-101084204-B Chemical synthesis and purification of diaminophenothiazinium compounds including methylene blue (MTC) WISTA LAB LTD 2012-12-05 CN disclosed
CN-101166719-B Bcrp/abcg2 inhibitor YAKULT HONSHA KK 2012-11-07 CN disclosed
CN-101043918-B Cationic azacyanine dyes and colorants containing said dyes PROCTER & GAMBLE 2010-05-26 CN disclosed
CN-101043918-A Cationic azacyanine dyes and colorants containing said dyes PROCTER & GAMBLE (US) 2007-09-26 CN disclosed
EP-0470581-B1 Aromatic diazo compounds, production method thereof and photosensitive compositions using the same TOYO GOSEI KOGYO KK (JP) 1998-01-07 EP disclosed
US-5206349-A Lithographic printing plates TOYO GOSEI KOGY CO., LTD. (JP) 1993-04-27 US disclosed
EP-0470581-A2 Aromatic diazo compounds, production method thereof and photosensitive compositions using the same TOYO GOSEI KOGYO CO., LTD. (JP) 1992-02-12 EP disclosed
US-RE33635-E Enzymatic assay method TOYO JOZO KABUSHIKI KAISHA (JP) 1991-07-09 US disclosed
US-4681841-A CONSUMING OXYGEN OR GENERATING A PIGMENT; MEASUREMENT BY AN OXYGEN ELECTRODE OR COLORIMETRIC ASSAY TOYO JOZO KABUSHIKI KAISHA (JP) 1987-07-21 US disclosed
US-4477563-A DEVELOPMENT INHIBITION RELEASING COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1984-10-16 US disclosed
US-4163670-A PYRAZOLONE COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1979-08-07 US disclosed
US-4144071-A DISPERSION IN HYDROPHILIC COLLOID LAYER OF HYDROQUINONE REDUCING AGENT AND COMPOUND CONTAINING HETEROCYCLICTHIO GROUP FUJI PHOTO FILM CO., LTD. (JP) 1979-03-13 US disclosed
US-4015988-A SILVER HALIDE EMULSION, DYE COUPLERS FUJI PHOTO FILM CO., LTD. (JA) 1977-04-05 US disclosed
US-3984245-A SILVER HALIDE EMULSION, DEVELOPMENT INHIBITOR, COLLOID, MULTILAYER FUJI PHOTO FILM CO., LTD. (JA) 1976-10-05 US disclosed
US-3961963-A HYDROQUINONE DERIVATIVE, DEVELOPMENT INHIBITOR FUJI PHOTO FILM CO., LTD. (JA) 1976-06-08 US disclosed
US-3930863-A MULTILAYER, HYDROQUINONE DERIVATIVES FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed