Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542624 | 0.86 | RAB9A (0.37) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL6966979 | 0.85 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8544776 | 0.84 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8540324 | 0.82 | RAB9A (0.40) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8546600 | 0.81 | NPSR1 (0.37) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8545562 | 0.80 | NPSR1 (0.37) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL7557759 | 0.76 | LTA4H (0.40) | SMN1; SMN2NPSR1CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL7561656 | 0.74 | LTA4H (0.43) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9061793 | 0.72 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8544730 | 0.72 | RARB (0.41) | NPC1RAB9ASMN1; SMN2HSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736078-B1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION | MINNESOTA MINING & MFG (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5474705-A | Electrooptical displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-12-12 | — | — | US | disclosed |