Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029383 | 0.88 | KCNA3 (0.41) | CYP19A1MEN1POLBKMT2A | |
| SCHEMBL8540177 | 0.88 | CYP19A1 (0.49) | CYP19A1QPCTTBXAS1HMOX1SIGMAR1 | |
| SCHEMBL8544284 | 0.85 | CYP19A1 (0.49) | CYP19A1TBXAS1HMOX1 | |
| SCHEMBL8538300 | 0.85 | GRIN2B (0.54) | CCR3SIGMAR1HRH3 | |
| SCHEMBL8543266 | 0.85 | CYP3A4 (0.52) | MEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL8546852 | 0.84 | GRIN2B (0.53) | TBXAS1CCR3SIGMAR1HRH3 | |
| SCHEMBL11377928 | 0.82 | CYP19A1 (0.66) | CYP19A1QPCTTBXAS1HMOX1 | |
| SCHEMBL8545375 | 0.82 | SIGMAR1 (0.59) | HMOX1CCR3MEN1KMT2ASIGMAR1 | |
| SCHEMBL8540293 | 0.81 | CPB1 (0.44) | QPCTTBXAS1POLB | |
| SCHEMBL9030298 | 0.81 | C5AR1 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |