Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545661 | 0.89 | GRIN2B (0.46) | CPB1GRIN2BTBXAS1FAAHTPSAB1 | |
| SCHEMBL8540403 | 0.87 | TBXAS1 (0.46) | CPB1GRIN2BTBXAS1FAAHCYP2D6 | |
| SCHEMBL8540312 | 0.86 | GRIN2B (0.55) | CPB1GRIN2BTBXAS1FAAHPOLB | |
| SCHEMBL8540305 | 0.86 | FKBP1A (0.52) | CPB1CYP2D6 | |
| SCHEMBL8699493 | 0.82 | PKM (0.55) | QPCTTBXAS1 | |
| SCHEMBL8540461 | 0.81 | CYP19A1 (0.46) | QPCTTBXAS1POLB | |
| SCHEMBL8538696 | 0.81 | FAAH (0.50) | CPB1GRIN2BTBXAS1FAAHPOLB | |
| SCHEMBL8541116 | 0.81 | FAAH (0.57) | CPB1GRIN2BTBXAS1FAAHTPSAB1 | |
| SCHEMBL9031024 | 0.78 | PKM (0.53) | CPB1GRIN2BFAAHPOLB | |
| SCHEMBL8541801 | 0.76 | GRIN2B (0.57) | GRIN2BTBXAS1FAAHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |