Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540473 | 1.00 | L3MBTL1 (0.33) | L3MBTL1CYP3A4CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL4339773 | 0.81 | CYP3A4 (0.34) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL25755212 | 0.77 | CA2 (0.39) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL4337694 | 0.75 | POLB (0.34) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL6592367 | 0.75 | TSHR (0.39) | L3MBTL1 | |
| SCHEMBL18730508 | 0.73 | ALDH1A1 (0.36) | CYP2C19TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2934387 | 0.73 | ALDH1A1 (0.36) | CYP2C19TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL20279978 | 0.73 | ALDH1A1 (0.37) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4335835 | 0.71 | PIK3CD (0.39) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11770289 | 0.70 | L3MBTL1 (0.34) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801249-A | Chiral auxiliaries | OXFORD ASYMMETRY INTERNATIONAL PLC (GB) | 1998-09-01 | — | — | US | disclosed |