Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539105 | 1.00 | KCNJ1 (0.51) | KCNJ1KCNH2MEN1KMT2AALDH1A1 | |
| SCHEMBL8539540 | 0.92 | MEN1 (0.53) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL8540937 | 0.90 | SLC6A2 (0.47) | KCNJ1KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8537850 | 0.88 | MEN1 (0.53) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL8536070 | 0.86 | MEN1 (0.48) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL8535566 | 0.86 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL8535949 | 0.86 | SLC6A2 (0.46) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8537749 | 0.85 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL8540907 | 0.85 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL8537719 | 0.84 | SLC6A2 (0.45) | ALDH1A1KDM4ESLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817489-A | BACTERICIDES, OR CHEMICAL INTERMEDIATES THEREOF; DRUG LIBRARIES | ISIS PHARMACEUTICALS, INC. (US) | 1998-10-06 | — | — | US | claimed |