Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.47 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.47 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.47 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539540 | 0.94 | MEN1 (0.53) | ALDH1A1KDM4ETDP1SIGMAR1MEN1 | |
| SCHEMBL8537850 | 0.91 | MEN1 (0.53) | ALDH1A1KDM4ETDP1SIGMAR1MEN1 | |
| SCHEMBL8536070 | 0.89 | MEN1 (0.48) | ALDH1A1KDM4ETDP1SIGMAR1MEN1 | |
| SCHEMBL8587999 | 0.88 | SIGMAR1 (0.48) | ALDH1A1KDM4ETDP1SIGMAR1MEN1 | |
| SCHEMBL8540907 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1SIGMAR1MEN1 | |
| SCHEMBL8537749 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1SIGMAR1MEN1 | |
| SCHEMBL8540476 | 0.86 | KCNJ1 (0.51) | ALDH1A1KDM4ETDP1SIGMAR1MEN1 | |
| SCHEMBL8539105 | 0.86 | KCNJ1 (0.51) | ALDH1A1KDM4ETDP1SIGMAR1MEN1 | |
| SCHEMBL8536918 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ESIGMAR1MEN1KMT2A | |
| SCHEMBL8537719 | 0.81 | SLC6A2 (0.45) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817489-A | BACTERICIDES, OR CHEMICAL INTERMEDIATES THEREOF; DRUG LIBRARIES | ISIS PHARMACEUTICALS, INC. (US) | 1998-10-06 | — | — | US | claimed |