Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535718 | 0.86 | HTR2A (0.34) | HTR2AHTR2CDRD2ADRA2AADRA2C | |
| SCHEMBL9735917 | 0.77 | HTR2A (0.39) | HTR2AHTR2CDRD2ADRA2AADRA2C | |
| SCHEMBL9141916 | 0.74 | HTR2A (0.36) | HTR2AHTR2CDRD2ADRA2AADRA2C | |
| SCHEMBL8540481 | 0.72 | HTR2B (0.33) | HTR2AHTR2CDRD2ADRA2AADRA2C | |
| SCHEMBL4848406 | 0.72 | HTR2A (0.32) | HTR2AHTR2CDRD2ADRA2AADRA2C | |
| SCHEMBL4020277 | 0.72 | HTR2A (0.32) | HTR2AHTR2CDRD2ADRA2AADRA2C | |
| SCHEMBL8537452 | 0.70 | TRPV1 (0.35) | HTR2AHTR2CDRD2ADRA2AADRA2C | |
| SCHEMBL8534900 | 0.68 | ABCB1 (0.41) | — | |
| SCHEMBL8535501 | 0.68 | ABCB1 (0.41) | — | |
| SCHEMBL8534906 | 0.68 | ABCB1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |