Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | TSPO | P30536 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898801 | 0.95 | HTR6 (0.58) | HTR6SRCAKR1C3AKR1C1LMNA | |
| SCHEMBL8545209 | 0.88 | HTR6 (0.53) | HTR6LMNAPSEN1PSEN2APH1B | |
| SCHEMBL12675369 | 0.87 | SRC (0.54) | HTR6SRCAKR1C3AKR1C1LMNA | |
| SCHEMBL13387230 | 0.85 | SRC (0.58) | HTR6SRCAKR1C3AKR1C1LMNA | |
| SCHEMBL12093313 | 0.85 | HTR6 (0.70) | HTR6SRCFABP3FABP4FABP5 | |
| SCHEMBL675512 | 0.82 | PTGDR2 (0.48) | HTR6SRCLMNA | |
| SCHEMBL24015624 | 0.81 | HTR6 (0.52) | HTR6SRCLMNA | |
| SCHEMBL8545151 | 0.80 | PSEN1 (0.59) | HTR6LMNAPSEN1PSEN2APH1B | |
| SCHEMBL30661141 | 0.79 | HTR6 (0.47) | HTR6LMNAPSEN1PSEN2APH1B | |
| SCHEMBL15910233 | 0.79 | HTR6 (0.47) | HTR6LMNAPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177350-A | Imidazole derivatives and pharmaceutical compositions thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1998-03-25 | — | — | CN | disclosed |
| EP-0820989-A1 | IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |