SCHEMBL8545151

SCHEMBL8545151

Cc1ccc(S(=O)(=O)n2c3ccccc3c3ccc(Br)cc32)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 2/20 0.59
PSEN2 P49810 2/20 0.59
APH1B Q8WW43 2/20 0.59
NCSTN Q92542 2/20 0.59
APH1A Q96BI3 2/20 0.59
PSENEN Q9NZ42 2/20 0.59
HTR6 P50406 6/20 0.52
AGTR1 P30556 3/20 0.50
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.48
GAA P10253 2/20 0.48
ALDH3A1 P30838 2/20 0.48
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PCSK9 Q8NBP7 1/20 0.46
NOD1 Q9Y239 2/20 0.46
CXCL8 P10145 1/20 0.46
NOD2 Q9HC29 1/20 0.46
KDM4E B2RXH2 1/20 0.46
UBE2N P61088 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8545209 0.92 HTR6 (0.53) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL9901345 0.87 PSEN1 (0.62) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL17297375 0.87 HTR6 (0.67) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29357508 0.87 HTR6 (0.67) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30661141 0.84 HTR6 (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL15910233 0.84 HTR6 (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13387230 0.84 SRC (0.58) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL18713502 0.82 HTR6 (0.58) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL16397416 0.82 PSEN1 (0.58) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL16398112 0.81 PSEN1 (0.57) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12250878-B2 Light-emitting diode and amine compound for the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-03-11 US disclosed
US-20220199910-A1 LIGHT-EMITTING DIODE AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-06-23 US disclosed
WO-2015088249-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 2015-06-18 WO disclosed
WO-2015088249-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 2015-06-18 WO disclosed
WO-2015009102-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 (KR) 2015-01-22 WO disclosed
WO-2015009102-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 (KR) 2015-01-22 WO disclosed
EP-0820989-A1 IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1998-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12250878-B2 Light-emitting diode and amine compound for the same CRY1, ALDH1A2, MAOA PSEN1 2367/4885PSEN2 2176/4885APH1B 675/4885
US-20220199910-A1 LIGHT-EMITTING DIODE AND AMINE COMPOUND FOR THE SAME CRY1, ALDH1A2, MAOA PSEN1 2367/4885PSEN2 2176/4885APH1B 675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.