SCHEMBL8545209

SCHEMBL8545209

Cc1ccc(S(=O)(=O)n2c3ccccc3c3cc(Br)ccc32)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 7/20 0.53
PSEN1 P49768 1/20 0.53
PSEN2 P49810 1/20 0.53
APH1B Q8WW43 1/20 0.53
NCSTN Q92542 1/20 0.53
APH1A Q96BI3 1/20 0.53
PSENEN Q9NZ42 1/20 0.53
AGTR1 P30556 3/20 0.50
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.48
GAA P10253 2/20 0.48
ALDH3A1 P30838 1/20 0.48
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PCSK9 Q8NBP7 1/20 0.46
CXCL8 P10145 1/20 0.46
NOD2 Q9HC29 1/20 0.46
NOD1 Q9Y239 1/20 0.46
KDM4E B2RXH2 1/20 0.46
UBE2N P61088 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30661141 0.93 HTR6 (0.47) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL15910233 0.93 HTR6 (0.47) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL8545151 0.92 PSEN1 (0.59) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL8540570 0.88 HTR6 (0.55) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL18713502 0.88 HTR6 (0.58) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL9901345 0.87 PSEN1 (0.62) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL29357508 0.87 HTR6 (0.67) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL17297375 0.87 HTR6 (0.67) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL1898801 0.84 HTR6 (0.58) HTR6LMNASMN1; SMN2CXCL8NOD1
SCHEMBL1278656 0.83 HTR6 (0.53) HTR6PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12245503-B2 Heterocyclic compound, light-emitting device including the same, and electronic apparatus including the light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2025-03-04 US disclosed
US-20230363256-A1 COMPOSITION, LIGHT-EMITTING DEVICE INCLUDING THE COMPOSITION, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-20230232714-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-20 US disclosed
US-20230232714-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-20 US disclosed
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
CN-111518106-B Organic compound and organic electroluminescent element comprising same 索路思高新材料有限公司 2022-12-06 CN disclosed
US-11450821-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2022-09-20 US disclosed
US-20220123229-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-21 US disclosed
CN-114300627-A Heterocyclic compound, light-emitting element including the same, and electronic device 三星显示有限公司 2022-04-08 CN disclosed
WO-2015195837-A1 EMISSIVE MATERIAL FOR ORGANIC EMITTING DIODES NITTO DENKO CORPORATION (JP) 2015-12-23 WO disclosed
WO-2015195837-A1 EMISSIVE MATERIAL FOR ORGANIC EMITTING DIODES NITTO DENKO CORPORATION (JP) 2015-12-23 WO disclosed
US-20150357582-A1 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT EMITTING DEVICE USING SAME KYULUX, INC. (JP) 2015-12-10 US disclosed
EP-2949724-A1 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT USING SAME Kyushu University, National University Corporation (JP) 2015-12-02 EP disclosed
EP-2949724-A1 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT USING SAME Kyushu University, National University Corporation (JP) 2015-12-02 EP disclosed
WO-2015156580-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2015-10-15 WO disclosed
US-20140332777-A1 PHOSPHORESCENT HOST MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2014-11-13 US disclosed
US-20140332777-A1 PHOSPHORESCENT HOST MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2014-11-13 US disclosed
WO-2014115743-A1 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT USING SAME 国立大学法人九州大学 (JP) 2014-07-31 WO disclosed
EP-0820989-A1 IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1998-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230232714-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME NFE2L2, CRY1, LAGE3 HTR6 4569/4885PSEN1 563/4885PSEN2 485/4885
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND CRY1, CYP1A1, NQO1 HTR6 2741/4885PSEN1 2279/4885PSEN2 3197/4885
US-20150357582-A1 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT EMITTING DEVICE USING SAME CRY1, CRY2, INTS9 HTR6 2035/4885PSEN1 2840/4885PSEN2 2955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.