Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829249 | 0.79 | NISCH (0.43) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL8539558 | 0.78 | TAAR1 (0.44) | TAAR1NISCHMTORADKAR | |
| SCHEMBL28067584 | 0.77 | GUSB (0.46) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL8536464 | 0.75 | TAAR1 (0.45) | TAAR1NISCHMTORADKALDH1A1 | |
| SCHEMBL9952337 | 0.74 | TAAR1 (0.44) | TAAR1NISCHMTORADKPARP1 | |
| SCHEMBL29360220 | 0.73 | CSNK1A1 (0.49) | TAAR1NISCHMTORADKALDH1A1 | |
| SCHEMBL773131 | 0.73 | CSNK1A1 (0.49) | TAAR1NISCHMTORADKALDH1A1 | |
| SCHEMBL7235096 | 0.73 | TAAR1 (0.49) | TAAR1NISCHMTORADKALDH1A1 | |
| SCHEMBL8536119 | 0.72 | TAAR1 (0.47) | TAAR1NISCHMTORADKALDH1A1 | |
| SCHEMBL24088238 | 0.72 | NISCH (0.40) | TAAR1NISCHMTORADKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |