SCHEMBL29360220

SCHEMBL29360220

FC(F)(F)c1ccccc1-c1ncc[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1A1 P48729 1/20 0.49
TYRO3 Q06418 1/20 0.49
DYRK1B Q9Y463 1/20 0.49
TAAR1 Q96RJ0 1/20 0.49
MTOR P42345 1/20 0.48
ADK P55263 1/20 0.48
NISCH Q9Y2I1 1/20 0.48
NPY5R Q15761 1/20 0.44
HSD11B1 P28845 1/20 0.42
CYP1A2 P05177 3/20 0.42
CYP3A4 P08684 2/20 0.42
ALDH1A1 P00352 2/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP2C19 P33261 1/20 0.42
SCN9A Q15858 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL773131 1.00 CSNK1A1 (0.49) CSNK1A1TYRO3DYRK1BTAAR1MTOR
SCHEMBL7235096 0.85 TAAR1 (0.49) CSNK1A1TYRO3DYRK1BTAAR1MTOR
SCHEMBL6002865 0.82 CSNK1A1 (0.49) CSNK1A1TYRO3DYRK1BTAAR1MTOR
SCHEMBL9287236 0.80 NISCH (0.64) CSNK1A1TYRO3DYRK1BTAAR1MTOR
SCHEMBL27838439 0.79 TRPA1 (0.43) TAAR1MTORADKNISCHTRPA1
SCHEMBL14886257 0.78 NISCH (0.61) CSNK1A1TYRO3DYRK1BTAAR1MTOR
SCHEMBL9377527 0.78 NISCH (0.50) CSNK1A1TYRO3DYRK1BTAAR1MTOR
SCHEMBL8536119 0.77 TAAR1 (0.47) TAAR1MTORADKNISCHALDH1A1
SCHEMBL1289114 0.76 NISCH (0.53) CSNK1A1TYRO3DYRK1BMTORADK
SCHEMBL29985833 0.76 NISCH (0.53) CSNK1A1TYRO3DYRK1BMTORADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP claimed
WO-2024161038-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY IMMUSMOL SAS (FR) 2024-08-08 WO claimed
CN-118290450-A Europium-aluminum-containing lithium adsorbent precursor and preparation method thereof 万华化学集团股份有限公司 2024-07-05 CN claimed
EP-4277592-A1 TOPICAL COMPOSITION Liliger Ltd (IL) 2023-11-22 EP claimed
WO-2022153308-A1 TOPICAL COMPOSITION RICH PSC LTD. (IL) 2022-07-21 WO claimed
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP disclosed
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-06-12 US disclosed
US-12187720-B2 Compounds for treatment of cancer UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-01-07 US disclosed
WO-2024161038-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY IMMUSMOL SAS (FR) 2024-08-08 WO disclosed
CN-118290450-A Europium-aluminum-containing lithium adsorbent precursor and preparation method thereof 万华化学集团股份有限公司 2024-07-05 CN disclosed
EP-4277592-A1 TOPICAL COMPOSITION Liliger Ltd (IL) 2023-11-22 EP disclosed
US-20230355500-A1 TOPICAL COMPOSITION LILIGER LTD (IL) 2023-11-09 US disclosed
WO-2022153308-A1 TOPICAL COMPOSITION RICH PSC LTD. (IL) 2022-07-21 WO disclosed
US-20220024912-A1 COMPOUNDS FOR TREATMENT OF CANCER Oncternal Therapeutics, Inc. (US) 2022-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12187720-B2 Compounds for treatment of cancer KLK3, BRDT, ACP3 CSNK1A1 2313/4885TYRO3 3028/4885DYRK1B 4348/4885
US-20220024912-A1 COMPOUNDS FOR TREATMENT OF CANCER KLK3, BRDT, ACP3 CSNK1A1 2313/4885TYRO3 3028/4885DYRK1B 4348/4885
US-20230355500-A1 TOPICAL COMPOSITION NOS1, NOS3, NOS2 CSNK1A1 968/4885TYRO3 1691/4885DYRK1B 2202/4885
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER KLK3, BRDT, ACP3 CSNK1A1 2313/4885TYRO3 3028/4885DYRK1B 4348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.