SCHEMBL854076

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8180075	0.82	NPC1 (0.60)	NPC1RAB9ANPSR1CTDSP1PTGS2
	SCHEMBL8553015	0.81	SMN1; SMN2 (0.47)	NAMPTHPGDNPC1RAB9ACTDSP1
	SCHEMBL6639389	0.80	RAB9A (0.61)	HPGDNPC1RAB9ACYP2C19ALDH1A1
	SCHEMBL29268969	0.78	NPC1 (0.55)	HPGDNPC1RAB9ACTDSP1PTGS2
	SCHEMBL618237	0.77	NAMPT (0.34)	NAMPTHPGDNPC1RAB9AIDH1
	SCHEMBL29167802	0.76	NAMPT (0.61)	NAMPTNPC1RAB9AALDH1A1
	SCHEMBL633936	0.76	NAMPT (0.61)	NAMPTNPC1RAB9AALDH1A1
	SCHEMBL13868569	0.76	NAMPT (0.61)	NAMPTNPC1RAB9AALDH1A1
	SCHEMBL20438257	0.76	EPHX1 (0.54)	ALDH1A1NPSR1
	SCHEMBL30049121	0.74	NAMPT (0.65)	NAMPTHPGDNPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.